You ask for some way of completely eradicating irritability. The inclination to irritability is given us to use against sin, and we were never meant to use it against our fellow men. When we do, we act contrary to our true nature.
Whoever is experienced in the spiritual interpretation of Scripture knows that the simplest passage is of a significance equal to that of the most abstruse passage, and that both are directed to the salvation of man.
Ponder the truth of Christian marriage: man and wife are one flesh! Does it not follow that they must share all their possessions? And yet you two haggle over this property! And why? Because of words!
Nothing so abets our secret destruction as conceit and self-satisfaction, or so cuts us off from God and provokes our chastisement at the hands of other men as grumbling, or so disposes us to sin as a disorderly life and talkativeness.
If the main goal of the repentant sinner should be total, light-bearing and blessed communion with God, then the main hindrance to this is the existence of the passions still active and working in him - the virtues being as yet unsealed in him - and the unrighteousness of his powers. Therefore his main work upon conversion and repentance should be the uprooting of the passions and sealing the virtues - in a word, correcting himself.
He who wishes to purify his faults purifies them with tears, and he who wishes to acquire virtues, acquires them with tears; for weeping is the way the Scriptures and our Fathers give us, when they say 'Weep!' Truly, there is no other way than this.
You must flee from sensual things. Verily, every time a man comes close to a struggle with sensuality, he is like a man standing at the edge of a deep lake, and the enemy throws him in whenever he likes. But if the man lives far from sensual things, he is like one who stands at a distance from the lake, so that even if the enemy entices him in order to throw him to the bottom, God sends him help at the very moment that the enemy is drawing him away and doing him violence.
Do not think that even here any one of us constantly enjoys consolation. No: here, as everywhere, flesh and mind are at war; here as everywhere, there is falling into pride and purification through humbling: here, as everywhere, we long for consolations but must learn to carry a weighty cross. This cross tests our love. Can we, do we love God even under the weight of the most bitter adversities?
When God is thanked, He gives us still further blessings, while we, by receiving His gifts, love Him all the more and through this love attain that divine wisdom whose beginning is the fear of God (cf. Prov. 1:7).
In general, loquacity opens the doors of the soul, and the devout warmth of the heart at once escapes. Empty talk does the same, but even more so… Empty talk is the door to criticism and slander, the spreader of false rumors and opinions, the sower of discord and strife. It stifles the taste for mental work and almost always serves as a cover for the absence of sound knowledge…
Set your sight on heaven and order every step of your life so that it will be a step in that direction. It seems to me that it is all so simple, and yet so all-embracing.
If we desire to acquire faith the foundation of all blessings, the door to God's mysteries, unflagging defeat of our enemies, the most necessary of all the virtues, the wings of prayer and the dwelling of God within the soul--we must endure every trial imposed by our enemies and by our many and various thoughts... if we forcibly triumph over the trials and temptations that befall us, it will not be we who are victorious, but Christ, Who is present in us through faith.
Such are the souls of the saints: they love their enemies more than themselves, and in this age and in the age to come they put their neighbor first in all things, even though because of his ill-will he may be their enemy.
It is always possible to make a new start by means of repentance. 'You fell,' it is written, 'now arise'(cf. Prov. 24:16). And if you fall again, then rise again, without despairing at all of your salvation, no matter what happens. So long as you do not surrender yourself willingly to the enemy, your patient endurance, combined with self-reproach, will suffice for your salvation. 'For at one time we ourselves went astray in our folly and disobedience,' says St. Paul. '... Yet He saved us, not because of any good things we had done, but in His mercy' (Tit. 3:3,5).
Wherever we are and whatever our circumstances, the enemy always tries to prevent us from actively responding to the call. Pray for help. For help that you may never fail to respond. And beware lest, having received help and having done the right deed because of it, you should grow proud and acquire the habit of condemning others, in the secret chambers of your heart. Beware! For this would make all the fruits of your good works wither.