You ask for some way of completely eradicating irritability. The inclination to irritability is given us to use against sin, and we were never meant to use it against our fellow men. When we do, we act contrary to our true nature.
The best medicine for pride, man’s greatest sickness of soul, is humility. Words cannot describe or explain it, but the Fathers say that he who strives hard to live according to the precepts of our Lord, and is fully aware of his own sins, acquires it steadily. Therefore be very careful never to think yourself good, or the least bit better than others.
What do we do when attacked by some criminal? We strike out at him and shout for help. Our cries are answered by the police, who then rescue us from danger. We must do the same in inner warfare with the passions. Filled with anger against them, call for assistance: Help me, O Lord! Jesus Christ, Son of God, save me! O God, make speed to save me! O Lord make haste to help me! Having thus called on the Lord, do not allow your attention to wander from Him, do not let it turn to what is happening within you, but go on standing before the Lord and imploring His help. This will make the enemy run away as though pursued by flames.
Even a pious person is not immune to spiritual sickness if he does not have a wise guide -- either a living person or a spiritual writer. This sickness is called prelest, or spiritual delusion, imagining oneself to be near to God and to the realm of the divine and supernatural. Even zealous ascetics in monasteries are sometimes subject to this delusion, but of course, laymen who are zealous in external struggles (podvigi) undergo it much more frequently. Surpassing their acquaintances in struggles of prayer and fasting, they imagine that they are seers of divine visions, or at least of dreams inspired by grace. In every event of their lives, they see special intentional directions from God or their guardian angel. And then they start imagining that they are God's elect, and often try to foretell the future. The Holy Fathers armed themselves against nothing so fiercely as against this sickness -- prelest.
God smiles on the compassionate heart. Every time a beggar knocks at your door, try to perceive Christ Himself under the humble disguise. Would you, under any circumstances, let Christ knock in vain? The moral qualities of the individual beggar have nothing to do with it; that is Christ's concern, not yours. Who are you to judge your brother? Christ is using the beggar’s hand and mouth to test your compassion of Himself. Will you fail Him?
Faith is the sincere confession that God, Who is worshipped in the Trinity, Who created all things and provides for all, saves us who are fallen, through the power of the death on the Cross of the incarnate Son of God, by the grace of the Most Holy Spirit in His Holy Church. The beginnings of renewal, which are established in this life, will appear in all their glory in the future age, in a way that the mind cannot comprehend nor the tongue express.
Compunction comes when you consider how much you have grieved God Who is so good, so sweet, so merciful, so kind, and entirely full of love; Who was crucified and suffered everything for us. When you meditate on these things and other things the Lord has suffered, they bring compunction.
Not one of us can boast of having acquired humility: our actions, the whole of our life, prove the contrary. And where there is a lack of humility, pride is always present. Where light is wanting, darkness reigns.
According to the teaching of the Fathers, any impression which, touching the heart, fills it with a great irritation, must come from the region of passions. Therefore impulses which spring from the heart should not be followed at once, but only after careful examination and fervent prayer. God preserve us from a blind heart! It is well known that passions do blind the heart and screen the shining sun of the mind that we should all strive to gaze at.
Faith is truly a gift, gained for us through Christ's advent. But this does not abolish our freedom or responsibility. God desires of us not only faith but action too.
Pray simply. Do not expect to find in your heart any remarkable gift of prayer. Consider yourself unworthy of it. Then you will find peace. Use the empty cold dryness of your prayer as food for your humility. Repeat constantly: I am not worthy; Lord, I am not worthy! But say it calmly; without agitation.
In preparing for battle, however, do not think that you will always be victorious. Often there will be only hardship that will bring nothing but affliction... Provide yourself with only one thing, strong courage: no matter what happens, stay with what you have begun... No matter how life goes, whatever successes and failures there are, you should give all of this over to God's will.
If the main goal of the repentant sinner should be total, light-bearing and blessed communion with God, then the main hindrance to this is the existence of the passions still active and working in him - the virtues being as yet unsealed in him - and the unrighteousness of his powers. Therefore his main work upon conversion and repentance should be the uprooting of the passions and sealing the virtues - in a word, correcting himself.