It is as necessary for a man to say the Jesus Prayer as it is for a ship in danger to send out steadily the S.O.S. signal: Lord Jesus Christ have mercy on me.
Wherever we are and whatever our circumstances, the enemy always tries to prevent us from actively responding to the call. Pray for help. For help that you may never fail to respond. And beware lest, having received help and having done the right deed because of it, you should grow proud and acquire the habit of condemning others, in the secret chambers of your heart. Beware! For this would make all the fruits of your good works wither.
The most important thing during illness is to offer to God patience and thanksgiving for His merciful visitations. Sickness purifies sins and gives one time to meditate on the past.
Condemn only yourself, and you will not be condemned at His second and awful coming. From your whole heart remit the sins of whoever sins before you, and your Father who is in heaven will remit your sins.
Behold, this is the true and the Christian humility. In this you will be able to achieve victory over every vice, by attributing to God rather than to yourself the fact that you have won.
When the door of steam baths is continually left open, the heat inside rapidly escapes through it; likewise the soul in its desire to say many things, dissipates the remembrance of God through the door of speech, even though everything it says may be good. Ideas of value always shun verbosity, being foreign to confusion and fantasy. Timely silence, then, is precious, for it is nothing less than the mother of the wisest thoughts.
The enemy constantly endeavors to awaken in the abyss of the human heart a great turmoil about trifles. This is one of his tricks to blind our soul to the sun of truth, Christ our Lord, hidden in the heart's core of every one of our neighbors.
One must clean the royal house from every impurity and adorn it with every beauty, then the king may enter into it. In a similar way one must cleanse the earth of the heart and uproot the weeds of sin and the passionate deeds and soften it with sorrows and the narrow way of life, sow in it the seed of virtue, water it with lamentation and tears, and only then does the fruit of dispassion and eternal life grow. For the Holy Spirit does not dwell in a man until he has been cleansed from passions of the soul and body. Only one thing may remain within a man, either the Holy Spirit or the passions. Where the Holy Spirit is, there the passions do not come near, and where the passions are, there the Holy Spirit does not dwell, but rather the evil one.
God smiles on the compassionate heart. Every time a beggar knocks at your door, try to perceive Christ Himself under the humble disguise. Would you, under any circumstances, let Christ knock in vain? The moral qualities of the individual beggar have nothing to do with it; that is Christ's concern, not yours. Who are you to judge your brother? Christ is using the beggar’s hand and mouth to test your compassion of Himself. Will you fail Him?
Bear this in mind: the Christian life is an unending spiritual fight. The wily enemy cleverly uses snares and arrows without number. Before some of us he spreads the lure of worldliness, the outer pride of pomp and circumstance, the cruder lusts-the lusts of the flesh. But those of us who are not attracted by any of this he leads up on to the peaks of subtler prides. Having got us there-to the high country of self-esteem-he causes a dark mist, the mist of the subtlest prides, to enshroud our intellect. Then he leads us, his blinded slaves, away from God, without our even suspecting it. Mark this too: it is not very hard for the simple sinner to come to hate his foul life and, leaving it, to fling himself on the mercy of God; but it is very hard for the subtler sinner-the self-sufficient one-to let a ray of divine love pierce the leather jacket of his self-righteousness... Humility is the only weapon that wards off all attacks, but it is difficult to fashion, and the art of using it is often misunderstood, particularly by those who lead an active, worldly life.
Most people desire and seek after prosperity in this life, and they strive to avoid sorrows. While that seems very good and pleasant, constant prosperity and good fortune do a person harm. He falls into a variety of passions and sins, and angers the Lord, while those who live a life of sorrow come closer to the Lord and more readily attain unto salvation, for the Lord called the life of happiness the broad path. The wide gates and the broad way lead to destruction, and many there be who take that way (Matthew 7:13). It is the narrow way and the strait gate which lead to life eternal, and few there be who find it (Matthew 7:14). Thus, according to His love for us, seeing the possible benefit [of sorrows] to those who are worthy, the Lord moves many off the broad road and puts them on the narrow, sorrowful path, so that in [their] patient endurance of sickness and sorrow, He might effect their salvation and grant them life eternal.
You ask for some way of completely eradicating irritability. The inclination to irritability is given us to use against sin, and we were never meant to use it against our fellow men. When we do, we act contrary to our true nature.