The lives of men are subject to drastic changes. These changes are gradual at times; at others, lightning quick. But even those of us who enjoy long years of opulence and fame can find no consolation, no gladness, unless our heart is illumined by the steady light of peace. It is this peace that we must seek, it is for this peace that we should pray. The peace that our Lord gave to His disciples and to all those who really have faith in him.
Wherever we are and whatever our circumstances, the enemy always tries to prevent us from actively responding to the call. Pray for help. For help that you may never fail to respond. And beware lest, having received help and having done the right deed because of it, you should grow proud and acquire the habit of condemning others, in the secret chambers of your heart. Beware! For this would make all the fruits of your good works wither.
A man may seem to be silent, but if his heart is condemning others, he is babbling ceaselessly. But there may be another who talks from morning till night and yet he is truly silent, that is, he says nothing that is not profitable.
A man cannot correct himself all of a sudden, but it is like pulling a barge - pull, pull, and let go, let go! Not all at once, but little by little. Do you know the mast on a ship? There is a pole to which is tied all of the ship’s lines. If you pull on it then everything gradually pulls. But if you take it all at once, you will ruin everything.
You ask for some way of completely eradicating irritability. The inclination to irritability is given us to use against sin, and we were never meant to use it against our fellow men. When we do, we act contrary to our true nature.
Your past and present torments and sufferings are poured down upon you to test your faith and 'steel' it; they also work to curb your lusts and passions. Humble yourself. God gives help to the humble. Judgment of others, insistence on their shortcomings, can only increase the bitterness of your sorrow. Choose the better part.
Remember always that, once we have decided consciously to strive after righteousness, we cannot escape catastrophes and sorrows, no matter where we are.
God's Scripture gives proof in numerous passages that man must undergo many disturbances in this life; and also that many consolations are at hand. With these, a spirit of sufficient vigor and awareness of the right should overcome present discomforts and look to those things that promise everlasting joy.
You describe how bitterly you regret the inefficacy of your prayers. Beware: to wish for consolation or revelation in prayer is a sure sign of pride. Pray humbly, in perfect simplicity, seeking salvation only through forgiveness, & having faith that God will extend to you His mercy - as He did to the publican.