There is a sin which is always 'unto death' [1 Jn 5:16]; the sin which we have not repented. Even a saint's prayers will not be heard for the unrepented sin. The person who repents correctly does not imagine that his sins are cancelled through his own effort; but knows that through this effort he makes peace with God.
Pray firstly to be purified of passions, secondly to be freed from ignorance and forgetfulness, and thirdly to be delivered from all temptation and forsaking.
He who wants to cross the spiritual sea is long-suffering, humble, vigilant and self-controlled. If he impetuously embarks on it without these four virtues, he agitates his heart, but cannot cross.
He who reveres the Lord does what is commanded, and if he commits some sin or disobeys Him, endures whatever he has to suffer for this as being his desert.
If you wish to be saved and 'to come unto the knowledge of the truth' (I Tim. 2:4), endeavor always to transcend sensible things, and through hope alone to cleave to God. Then you will find principalities and powers fighting against you (Eph. 6:12), deflecting you against your will and provoking you to sin. But if you prevail over them through prayer and maintain your hope, you will receive God's grace, and this will deliver you...
The abstinent withdraws from gluttony, the uncovetous from covetousness, the silent from wordiness, the pure from attachment to sensory pleasures, the chaste from fornication, he who is content with what he has from love of money, the meek from agitation (anger), the humble from vanity, the obedient from objection, he who is honest with himself from hypocrisy; equally, he who prays withdraws from despair, the willing pauper from acquisitiveness, he who professes his faith from denying it, the martyr from idolatry – so you see that each virtue, performed even unto death, is nothing but withdrawal from sin; and withdrawal from sin is a natural action, not an action which could be rewarded by the kingdom.
Rivalry over material possessions has made us forget the counsel of the Lord, who urged us to take no thought for earthly things, but to seek only the kingdom of heaven (cf. Matt. 6:33).
Put aside bodily considerations when you stand in prayer, lest the bite of a flea, a gnat or a fly deprive you of the greatest gain afforded by prayer.