St. John Climacus was asked if there are reliable signs by which it's possible to know whether a soul is drawing near to God or moving away from Him. After all, regarding ordinary things there are clear signs as to whether they're good or not. When, for instance, cabbage, meat or fish begins to rot, it's easy to notice it, since the rotting object begins to give off a foul odor, the color and taste change, and its external appearance witnesses to its deterioration. Well, and what about the soul? After all, it's bodiless and can't give off a bad smell or change its appearance. To this question the Holy Father replies, 'A sure sign of the deadening of the soul is the avoidance of church services.'
Do not neglect the practice of the virtues; if you do, your spiritual knowledge will decrease, and when famine occurs you will go down into Egypt (Genesis 41:57, 46:6).
In patience is the assembly of all the virtues by which our souls are saved, as St. Ephraim says: He who acquires patience touches on every virtue; for he rejoices in sorrows, is well tested in misfortunes, is glad in perils, is ready for obedience, is filled with love, gives praise when provoked, is humble when reproached, is unwavering in misfortunes.