You ask for some way of completely eradicating irritability. The inclination to irritability is given us to use against sin, and we were never meant to use it against our fellow men. When we do, we act contrary to our true nature.
According to the blameless faith of the Christians which we have obtained from God, I confess and agree that I believe in one God the Father Almighty; God the Father, God the Son, God the Holy Ghost; I adore and worship one God, the Three. I confess to the oeconomy of the Son in the flesh, and that the holy Mary, who gave birth to Him according to the flesh, was Mother of God. I acknowledge also the holy apostles, prophets, and martyrs; and I invoke them to supplication to God, that through them, that is, through their mediation, the merciful God may be propitious to me, and that a ransom may be made and given me for my sins. Wherefore also I honour and kiss the features of their images, inasmuch as they have been handed down from the holy apostles, and are not forbidden, but are in all our churches.
When God, using our conscience, calls us to righteousness and yet our self-will opposes Him, He respects our freedom and lets our own will be done; but then, alas, our minds grow dull, our will slack, and we commit iniquities without number. On the other hand, the fruits of the spirit are soon granted to them who follow the commandments of Christ our Lord.
The most important thing during illness is to offer to God patience and thanksgiving for His merciful visitations. Sickness purifies sins and gives one time to meditate on the past.
One cannot approach the knowledge of the truth with a disturbed heart. Therefore we must try to avoid everything that disturbs our heart, that causes forgetfulness, excitement or passion, or that awakens unrest. We must free ourselves as much as possible from all fuss and flutter and ado over vain things. Yes, when we serve the Lord we shall not be troubled about many things, but always keep in mind that one thing is needful (Luke 10:41).
Solitude offers us an excellent opportunity for calming our passions and giving our reason time to remove them thoroughly from our soul. For just as wild animals can be soothed by being stroked, so all our anger, fear and stress, which poison and disrupt our soul, can be soothed by an atmosphere of peace where the freedom from constant disturbance ensures that our soul can be brought more easily under the power of reason.
Fasting was ordained in Paradise. The first injunction was delivered to Adam, ‘Of the tree of the knowledge of good and evil you shall not eat.’ ‘You shall not eat’ is a law of fasting and abstinence. The general argument is rather against excess than in support of ceremonial abstinence. In Paradise there was no wine, no butchery of beasts, no eating of flesh. Wine came in after the flood. Noah became drunk because wine was new to him. So fasting is older than drunkenness. Esau was defiled, and made his brother’s slave, for the sake of a single meal. It was fasting and prayer which gave Samuel to Hannah. Fasting brought forth Samson. Fasting begets prophets, strengthens strong men. Fasting makes lawgivers wise, is the soul’s safeguard, the body’s trusty comrade, the armor of the champion, the training of the athlete.
Dearly Beloved, each word and deed of our Savior Jesus Christ is for us a lesson in virtue and piety. For this end also did He assume our nature, so that every man and every woman, contemplating as in a picture the practice of all virtue and piety, might strive with all their hearts to imitate His example. For this He bore our body, so that as far as we could we might repeat within us the manner of His Life. And so therefore, when you hear mention of some word or deed of His, take care not to receive it simply as something that incidentally happened, but raise your mind upwards towards the sublimity of what He is teaching, and strive to see what has been mystically handed down to us.
We should indeed be the strangest people if we were to find any pleasure in the schisms and divisions that beset the Church, and if we did not consider it as the greatest achievement to see the scattered limbs of Christ reassembled once more. Our desire to achieve this is as strong as the knowledge of our weakness to do so.
The enemy constantly endeavors to awaken in the abyss of the human heart a great turmoil about trifles. This is one of his tricks to blind our soul to the sun of truth, Christ our Lord, hidden in the heart's core of every one of our neighbors.
Trials are of two kinds. Either affliction will test our souls as gold is tried in a furnace, and make trial of us through patience, or the very prosperity of our lives will oftentimes, for many, be itself an occasion of trial and temptation. For it is equally difficult to keep the soul upright and undefeated in the midst of afflictions, as to keep oneself from insolence and pride in prosperity.
Even a pious person is not immune to spiritual sickness if he does not have a wise guide -- either a living person or a spiritual writer. This sickness is called prelest, or spiritual delusion, imagining oneself to be near to God and to the realm of the divine and supernatural. Even zealous ascetics in monasteries are sometimes subject to this delusion, but of course, laymen who are zealous in external struggles (podvigi) undergo it much more frequently. Surpassing their acquaintances in struggles of prayer and fasting, they imagine that they are seers of divine visions, or at least of dreams inspired by grace. In every event of their lives, they see special intentional directions from God or their guardian angel. And then they start imagining that they are God's elect, and often try to foretell the future. The Holy Fathers armed themselves against nothing so fiercely as against this sickness -- prelest.
Keep your mind from malicious thoughts of your neighbors, knowing that such thoughts are hurled by diabolical power, to keep your mind from your own sins and from seeking.
Wherever we are and whatever our circumstances, the enemy always tries to prevent us from actively responding to the call. Pray for help. For help that you may never fail to respond. And beware lest, having received help and having done the right deed because of it, you should grow proud and acquire the habit of condemning others, in the secret chambers of your heart. Beware! For this would make all the fruits of your good works wither.