The most important thing during illness is to offer to God patience and thanksgiving for His merciful visitations. Sickness purifies sins and gives one time to meditate on the past.
Dr. George Bebis writes that 'In one of his letters, St. Basil [the Great] explicitly writes that he accepts the intercession of the apostles, prophets and martyrs, and he seeks their prayers to God. (Letter 360) Then, speaking about the Forty Martyrs, who suffered martyrdom for Christ, he emphasizes that they are common friends of the human race, strong ambassadors and collaborators in fervent prayers. (Chapter 8) St. Gregory of Nyssa asks St. Theodore the Martyr... to fervently pray to our Common King, our God, for the country and the people (Encomium to Martyr Theodore).'
The undefiled beauty of fasting is the pure mother of character. It causes philosophy to gush forth, and offers a crown. It negotiates Paradise for us and grants a paternal family for those who fast. Of this Adam was deprived, and he attracted death, when he dishonored the worth of feasting. For at the time when it was treated scornfully, the God of all, the Creator and the Master was at once displeased. To those who honor it He grants eternal life.
Those who have sinned must not despair. Let that never be. For we are condemned not for the multitude of evils, but because we do not want to repent...
Ponder the truth of Christian marriage: man and wife are one flesh! Does it not follow that they must share all their possessions? And yet you two haggle over this property! And why? Because of words!
A man is neither saved nor lost by the place he is in, but is saved or lost by his deeds. Neither a holy place nor a holy state is of use to him who does not fulfill the commandments of the Lord.
There is a sin which is always 'unto death' [1 Jn 5:16]; the sin which we have not repented. Even a saint's prayers will not be heard for the unrepented sin. The person who repents correctly does not imagine that his sins are cancelled through his own effort; but knows that through this effort he makes peace with God.
Keep your conscience keen and bright, and refrain from hankering after, or expecting, consolation. Leave that to God. He knows when, where, and how to give it to you.
He who reveres the Lord does what is commanded, and if he commits some sin or disobeys Him, endures whatever he has to suffer for this as being his desert.
The lives of men are subject to drastic changes. These changes are gradual at times; at others, lightning quick. But even those of us who enjoy long years of opulence and fame can find no consolation, no gladness, unless our heart is illumined by the steady light of peace. It is this peace that we must seek, it is for this peace that we should pray. The peace that our Lord gave to His disciples and to all those who really have faith in him.
The Lord commands all men to repent (Matt. 4:17), so that even the spiritual and those making progress should not neglect this injunction and fail to give attention to the smallest and most subtle errors.
You ask for some way of completely eradicating irritability. The inclination to irritability is given us to use against sin, and we were never meant to use it against our fellow men. When we do, we act contrary to our true nature.
In answer to your question as to what constitutes a happy life, whether splendor, fame and wealth, or a quiet, peaceful, family life, I will say that I agree with the latter, but will add the following: A life lived in humility and with an irreproachable conscience brings peace, tranquility, and true happiness. But wealth, honor, glory and exalted position often serve as the cause of a multitude of sins, and such happiness is not one on which to rely.
Sear your loins by abstaining from food, and prove your heart by controlling your speech, and you will succeed in bringing the desiring and incensive powers of your soul into the service of what is noble and good.
Every tribulation reveals the state of our will, whether it inclines to the right or to the left. An unexpected tribulation is called temptation, because it subjects a man to a test of his secret dispositions.