When you are praying alone, and your spirit is dejected, and you are wearied and oppressed by your loneliness, remember then, as always, that God the Trinity looks upon you with eyes brighter than the sun; also all the angels, your own Guardian Angel, and all the Saints of God. Truly they do; for they are all one in God, and where God is, there are they also. Where the sun is, thither also are directed all its rays. Try to understand what this means.
Before the war begins, seek out your ally; before you fall ill, seek out your physician; and before grievous things come upon you, pray, and in the time of your tribulations you will find Him, and He will listen to you.
O man, learn the humility of Christ and the Lord will give you to taste of the sweetness of prayer. And if you would pray cleanly, be humble and temperate, confess yourself thoroughly, and prayer will feel at home in you. Be obedient, submit with a good conscience to those in authority; be content with all things, and your mind will be cleansed of vain thoughts. Remember that the Lord sees you, and be fearful lest you anywise offend your brother, whom neither dispraise nor grieve, even by a look, and the Holy Spirit will love you and will Himself be your help in all things.
What does it mean to be as wise as a serpent? When a serpent is attacked, it is willing to have much of its body severed, as long as it saves the head. So to be wise as a serpent means to be willing to lose everything - your wealth, your reputation, your friends - as long as you save your faith. Your faith is your head, by which you learn all truth; and by that truth your soul is set free. We should, however, recognize that the wisdom of the serpent is not enough; we must be honest and innocent as doves. Indeed it is the combination of wisdom and innocence that creates virtue. The person who is wise as a serpent can sustain the most terrible attacks and still continue to flourish as a disciple of Christ. The person who is innocent refuses to retaliate against those who make the attacks. To be as innocent as a dove means never to take revenge on those who wrong you or undermine you. Unless wisdom is tempered by innocence, one attack provokes another, and conflict continues without end. Unless innocence is tempered by wisdom, a person is so vulnerable that he will not even survive a single attack. Rest assured that no one can ever take away your faith; your wisdom guards against that. But be careful never to bear a grudge against anyone who does you wrong.
Unceasing prayer means to have the mind always turned to God with great love, holding alive our hope in Him, having confidence in Him whatever we are doing and whatever happens to us. That is the attitude that the Apostle had when he wrote: ‘Who shall separate us from the love of Christ? Shall tribulation, or distress, or persecution, or famine, or nakedness, or peril? Neither death nor life nor any other creature shall be able to separate us from the love of God in Christ Jesus.’ [cf. Rom. 8:35-38]
The most important thing in any good effort and the height of all activities is to persevere in prayer, by means of which we can always acquire through supplication the other virtues from God as well.
And when you pray, see that you ask not for what is alien to your life, and provoke the Lord. Ask not for money, not for human glory, nor power, nor for any of the things that pass away. But seek for the kingdom of God, and all that is needed for your body will be provided; as the Lord Himself has said: Seek ye the kingdom of God, and his justice, and all these things will be added unto you (Matthew 6:33).
Pray simply. Do not expect to find in your heart any remarkable gift of prayer. Consider yourself unworthy of it. Then you will find peace. Use the empty cold dryness of your prayer as food for your humility. Repeat constantly: I am not worthy; Lord, I am not worthy! But say it calmly; without agitation.
Both public and private prayer are necessary in order that we may lead a truly Christian life, and that the life of the spirit should not become extinct in us. It is indispensable that we should attend divine service in church with faith, zeal and understanding, just as it is indispensable to provide a lamp with fuel or power if it is to burn and not to go out.
How can one avoid distractions in prayer? If one abides in the presence of God. Indeed, when in the presence of one's judge and one's master, and speaking with him, one does not let one's eyes wander elsewhere. How much more should the one who approaches the Lord never turn away the eye of his heart, but fix it on Him who searches the reins and the heart.
You describe how bitterly you regret the inefficacy of your prayers. Beware: to wish for consolation or revelation in prayer is a sure sign of pride. Pray humbly, in perfect simplicity, seeking salvation only through forgiveness, & having faith that God will extend to you His mercy - as He did to the publican.
The evil spirit tries to scatter prayer as if it were a sand heap, tries to turn the words into dry sand, without coherency or moisture - that is to say, without fervor of heart. Thus prayer may become either a house built on sand or a house built on a rock. Those build on sand who pray without faith, absently, coldly: such prayer is scattered of itself, and does not bring any profit to him who prays; those build on a rock who, during the whole time of their prayer, have their eyes fixed upon God, and pray to Him as to a living person, conversing face to face with them.
Wherever we are and whatever our circumstances, the enemy always tries to prevent us from actively responding to the call. Pray for help. For help that you may never fail to respond. And beware lest, having received help and having done the right deed because of it, you should grow proud and acquire the habit of condemning others, in the secret chambers of your heart. Beware! For this would make all the fruits of your good works wither.
Tedium is the granddaughter of despondency, and the daughter of slothfulness. In order to drive it away, labor at your work, and do not be slothful in prayer. The tedium will pass, and zeal will come. And if to this you add patience and humility, then you will be rid of all misfortunes and evils.