The vain desires of this world separate us from our homeland; love of them and habit clothe our soul as if in a hideous garment. We, traveling on the journey of this life and calling on God to help us, ought to be divesting ourselves of this hideous garment and clothing ourselves in new desires, in a new love of the age to come, and thereby to receive knowledge of how near or how far we are from our heavenly homeland.
We ought not to grieve or become irritated at anything because, by frequent vexation and irritability, we form the morally and physically very injurious habit of irritability, whilst by bearing opposition with equanimity we form the good and useful habit of enduring everything calmly and patiently.
You ask for some way of completely eradicating irritability. The inclination to irritability is given us to use against sin, and we were never meant to use it against our fellow men. When we do, we act contrary to our true nature.