You ask for some way of completely eradicating irritability. The inclination to irritability is given us to use against sin, and we were never meant to use it against our fellow men. When we do, we act contrary to our true nature.
The dread Mysteries, full of such great salvation, which are celebrated at every Liturgy, are also called a Thanksgiving [Eucharistia] because they are the remembrance of many benefits, and they signify the culmination of God's Providence towards us, and in every way cause us to be thankful to Him.
We ought not to grieve or become irritated at anything because, by frequent vexation and irritability, we form the morally and physically very injurious habit of irritability, whilst by bearing opposition with equanimity we form the good and useful habit of enduring everything calmly and patiently.