We ought not to grieve or become irritated at anything because, by frequent vexation and irritability, we form the morally and physically very injurious habit of irritability, whilst by bearing opposition with equanimity we form the good and useful habit of enduring everything calmly and patiently.
You ask for some way of completely eradicating irritability. The inclination to irritability is given us to use against sin, and we were never meant to use it against our fellow men. When we do, we act contrary to our true nature.
If you are a friend of Christ you should have as friends persons who are of benefit to you and contribute to your way of life. Let your friends be men of peace, spiritual brethren, holy fathers. It is of such that our Lord was speaking when He said: 'My mother and brethren are those who do the will of My Father who is in heaven.' (cf. Matt. 12:49-50).