You ask for some way of completely eradicating irritability. The inclination to irritability is given us to use against sin, and we were never meant to use it against our fellow men. When we do, we act contrary to our true nature.
We ought not to grieve or become irritated at anything because, by frequent vexation and irritability, we form the morally and physically very injurious habit of irritability, whilst by bearing opposition with equanimity we form the good and useful habit of enduring everything calmly and patiently.
The most important thing during illness is to offer to God patience and thanksgiving for His merciful visitations. Sickness purifies sins and gives one time to meditate on the past.
