The best medicine for pride, man’s greatest sickness of soul, is humility. Words cannot describe or explain it, but the Fathers say that he who strives hard to live according to the precepts of our Lord, and is fully aware of his own sins, acquires it steadily. Therefore be very careful never to think yourself good, or the least bit better than others.
You ask for some way of completely eradicating irritability. The inclination to irritability is given us to use against sin, and we were never meant to use it against our fellow men. When we do, we act contrary to our true nature.
Remember that a good action is always either preceded or followed by temptations. God permits this so that the virtue, exercised in that particular action, may be confirmed, consolidated, steeled.
With such a welcome does the representation of the Virgin's form cheer us, inviting us to draw not from a bowl of wine, but from a fair spectacle, by which the rational part of our soul, being watered through our bodily eyes, and given eyesight in its growth towards the divine love of Orthodoxy, puts forth in the way of fruit the most exact vision of truth. Thus, even in her images does the Virgin's grace delight, comfort and strengthen us! A virgin mother carrying in her pure arms, for the common salvation of our kind, the common Creator reclining as an infant - that great and ineffable mystery of the Dispensation! A virgin mother, with a virgin's and a mother's gaze, dividing in indivisible form her temperament between both capacities, yet belittling neither by its incompleteness.
The passion of self-esteem is a three-pronged barb heated and forged by the demons out of vanity, presumption and arrogance. Yet those who dwell under the protection of the God of heaven (cf. Ps. 91.1) detect it easily and shatter its prongs, for through their humility they rise above such vices and find repose in the tree of life.
A life lived in the world can be as good, in the eyes of God, as one spent in a monastery. It is indeed only the keeping of God's commandments, love of all, and a true sense of humility that matter, wherever we are.
God smiles on the compassionate heart. Every time a beggar knocks at your door, try to perceive Christ Himself under the humble disguise. Would you, under any circumstances, let Christ knock in vain? The moral qualities of the individual beggar have nothing to do with it; that is Christ's concern, not yours. Who are you to judge your brother? Christ is using the beggar’s hand and mouth to test your compassion of Himself. Will you fail Him?
Do not think that even here any one of us constantly enjoys consolation. No: here, as everywhere, flesh and mind are at war; here as everywhere, there is falling into pride and purification through humbling: here, as everywhere, we long for consolations but must learn to carry a weighty cross. This cross tests our love. Can we, do we love God even under the weight of the most bitter adversities?
You are, I am sure, aware that for you penitence is now no longer limited to disclosing your sins to your confessor, but that you must now bear your sins in mind always, until your heart nearly breaks with their ugly load; and would break, were it not for your firm faith in the mercy of our Lord.
In answer to your question as to what constitutes a happy life, whether splendor, fame and wealth, or a quiet, peaceful, family life, I will say that I agree with the latter, but will add the following: A life lived in humility and with an irreproachable conscience brings peace, tranquility, and true happiness. But wealth, honor, glory and exalted position often serve as the cause of a multitude of sins, and such happiness is not one on which to rely.
According to the teaching of the Fathers, any impression which, touching the heart, fills it with a great irritation, must come from the region of passions. Therefore impulses which spring from the heart should not be followed at once, but only after careful examination and fervent prayer. God preserve us from a blind heart! It is well known that passions do blind the heart and screen the shining sun of the mind that we should all strive to gaze at.
The joint prayer of husband and wife is a great force. That may be one of the reasons why the enemy is trying to get both of you to break this excellent habit. [This is] one more temptation which God permits so that you should learn to overcome it and come out of the testing stronger than before!
Confirm yourself in this truth: that every Divine writing that is in agreement with the path of salvation instructs, teaches, chastises, and strengthens, that our path might be ever according to God.
The most important thing during illness is to offer to God patience and thanksgiving for His merciful visitations. Sickness purifies sins and gives one time to meditate on the past.