The Antichrist will not rule over all, but only over those who are worthy of perdition, who, even if he did not come, still would have deprived themselves of salvation.
The Antichrist must be understood as spiritual phenomenon..., why will everyone in the world want to bow down to him, obviously it is because there is something in him that responds to something in us, that something being lack of Christ in us, if we will bow down to him (God forbid that we do so) it will be because we feel an attraction to some kind of external thing which might even look like Christianity since Antichrist means the one that is in place of Christ or looks like Christ.
Having filled himself with pride, the Antichrist will begin to set himself up and glorify himself as God, belching forth slander against Christ. He will do this so openly that he will command that all those who do not want to serve him as God be killed.
We firmly believe that the Church will never fall, will never waiver and will not be destroyed. For this is what Christ taught, by Whom the heavens were established and the earth was founded, and stands firmly as the Holy Spirit says” (Ps. 32:6). The Antichrist will lure to himself 'those who have a weak and feeble mind, will seduce and will tear them away from the living God.'
The adversary will sit in the temple of Jerusalem, in order to show himself as Christ, he will demand that those who are captivated by him should worship him as Christ. The Antichrist will demand worship as if he were God.
St. John Chrysostom, in considering the misfortune both of parents that neglect the good upbringing of their children and of the children not well brought up, says this, 'Parents that neglect to bring up their children as Christians, are most heinous murderers of children' (Homily 3, 'Against Those that Slander the Monastic Life '). For child-killers separate the body from the soul, but these parents cast them both soul and body info fiery Gehenna. It is impossible to escape from the former death according to natural law, but it would be possible to escape from the latter death were the negligence of the parents not to blame for it. Moreover, once it comes, the Resurrection is able to abolish bodily death, but nothing can overturn spiritual destruction. Therefore, parents, listen to the word of the Lord, 'Bring up your children in the nurture and admonition of the Lord' (Eph. 6:4).
Guard thyself then, O man; thou hast the signs of Antichrist; and remember them not only thyself, but impart them also freely to all. If thou hast a child according to the flesh, admonish him of this now; if thou hast begotten one through catechizing, put him also on his guard, lest he receive the false one as the True. For the mystery of iniquity doth already work. I fear these wars of the nations; I fear the schisms of the Churches; I fear the mutual hatred of the brethren. But enough on this subject; only God forbid that it should be fulfilled in our days; nevertheless, let us be on our guard. And thus much concerning Antichrist.
I say that martyrs of that time excel all martyrs, for martyrs hitherto have wrestled with men only, but in the time of the Antichrist they shall battle with Satan in his own person.
For the Antichrist will come for the destruction of men, and to injure them, for what will he not then work? He will change and confound all things, both by his commandments and by the fear of him. He will be terrible in every way: by his power and by his unlawful commandments.’
The Antichrist will not only pronounce himself highest of the false gods, but will sit in the Temple of God, as if he were God ... the Jews, who did not want to believe in the Lord, as though He were an adversary to God, will believe in the Antichrist who will pronounce himself to be the god of all.
He who has not received within himself the kingdom of God cannot recognize the Antichrist. He is absolutely sure to become in a way incomprehensible to himself his follower.
God will allow persecution from the Antichrist not because He cannot stop it, but because He desires, as usual, His strugglers to be crowned, and for this reason, the reverent ones among the living will be taken up into the clouds, receiving, as a reward of honor, that which is higher than any man.